VARSITY: Entyvio® (vedolizumab) vs adalimumab for moderate-to-severe ulcerative colitis (UC)
VARSITY is the first head-to-head trial evaluating the efficacy and safety of Entyvio® with adalimumab in patients with moderate-to-severe ulcerative colitis (UC). Enrolled patients had failed conventional therapies and were either biologic-naïve or had failed an anti-TNFα inhibitor.1
The results from this trial demonstrated that Entyvio® was superior to adalimumab with respect to achievement of clinical remission and endoscopic improvement at Week 52.1 Explore the data further by viewing the vignette below.
Explore the VARSITY trial vignette
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References:
- Sands BE, et al. N Engl J Med 2019;381:1215–1226